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US Patent 12110277 Synthesis of nirogacestat

Patent 12110277 was granted and assigned to SpringWorks Therapeutics on October, 2024 by the United States Patent and Trademark Office.

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Patent attributes

Patent Applicant

SpringWorks Therapeutics

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Current Assignee

SpringWorks Therapeutics

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Patent Jurisdiction

United States Patent and Trademark Office

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Patent Number

Patent Inventor Names

Mark Hatcher0

Kristin Patterson0

Date of Patent

October 8, 2024

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Patent Application Number

179291530

Date Filed

September 1, 2022

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Patent Citations

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US Patent 10590087 Solid state forms of (S)-2-(((S)-6,8-difluoro-1,2,3,4-tetrahydronaphthalen-2-yl)amino)-N-(1-(2-methyl-1-(neopentylamino)propan-2-yl)-1H-imidazol-4-yl)pentanamide and uses thereof

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US Patent 10710966 Solid state forms of (S)-2-(((S)-6,8-difluoro-1,2,3,4-tetrahydronaphthalen-2-yl)amino)-N-(1-(2-methyl-1-(neopentylamino)propan-2-yl)-1H-imidazol-4-yl)pentanamide and uses thereof

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Patent Primary Examiner

Samantha L Shterengarts

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Patent abstract

The present disclosures are directed to processes for synthesizing (S)-2-(((S)-6,8-difluoro-1,2,3,4-tetrahydronaphthalen-2-yl)amino)-N-(1-(2-methyl-1-(neopentylamino)propan-2-yl)-1H-imidazol-4-yl)pentanamide (“nirogacestat”).

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