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US Patent 12110277 Synthesis of nirogacestat

Patent 12110277 was granted and assigned to SpringWorks Therapeutics on October, 2024 by the United States Patent and Trademark Office.

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 US Patent 12110277 Synthesis of nirogacestat

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Patent abstract

The present disclosures are directed to processes for synthesizing (S)-2-(((S)-6,8-difluoro-1,2,3,4-tetrahydronaphthalen-2-yl)amino)-N-(1-(2-methyl-1-(neopentylamino)propan-2-yl)-1H-imidazol-4-yl)pentanamide (“nirogacestat”).

Infobox
Is a
Patent
Patent
0
Patent Applicant
SpringWorks Therapeutics
SpringWorks Therapeutics
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Current Assignee
SpringWorks Therapeutics
SpringWorks Therapeutics
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Patent Jurisdiction
United States Patent and Trademark Office
United States Patent and Trademark Office
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Patent Number
121102770
Patent Inventor Names
Kristin Patterson0
Mark Hatcher0
Date of Patent
October 8, 2024
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Patent Application Number
179291530
Date Filed
September 1, 2022
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Patent Citations
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US Patent 7951958 Imidazole compounds for the treatment of neurodegenerative disorders
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US Patent 10590087 Solid state forms of (S)-2-(((S)-6,8-difluoro-1,2,3,4-tetrahydronaphthalen-2-yl)amino)-N-(1-(2-methyl-1-(neopentylamino)propan-2-yl)-1H-imidazol-4-yl)pentanamide and uses thereof
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US Patent 10710966 Solid state forms of (S)-2-(((S)-6,8-difluoro-1,2,3,4-tetrahydronaphthalen-2-yl)amino)-N-(1-(2-methyl-1-(neopentylamino)propan-2-yl)-1H-imidazol-4-yl)pentanamide and uses thereof
0
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US Patent 10941118 Solid state forms of (S)-2-(((S)-6,8-difluoro-1,2,3,4-tetrahydronaphthalen-2-yl)amino)-N-(1-(2-methyl-1-(neopentylamino)propan-2-yl)-1H-imidazol-4-yl)pentanamide and uses thereof
0
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US Patent 11504354 Chlorinated tetralin compounds and pharmaceutical compositions
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Patent Primary Examiner
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Samantha L Shterengarts
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