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US Patent 12121590 Pyrrolobenzodiazepines and conjugates thereof

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 US Patent 12121590 Pyrrolobenzodiazepines and conjugates thereof

Infobox
Is a
Patent
Patent
0
Patent Jurisdiction
United States Patent and Trademark Office
United States Patent and Trademark Office
0
Patent Number
121215900
Patent Inventor Names
Philip Wilson Howard0
Date of Patent
October 22, 2024
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Patent Application Number
183296810
Date Filed
June 6, 2023
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Patent Citations
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US Patent 7223837 Elongated and multiple spacers in activatible prodrugs
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US Patent 7244724 Pyrrolobenzodiazepines
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US Patent 7265105 Pyrrolobenzodiazepines
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US Patent 7375078 Heterocyclic self-immolative linkers and conjugates
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US Patent 7407951 Pyrrolobenzodiazepines
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US Patent 7429658 Synthesis of protected pyrrolobenzodiazepines
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US Patent 7511032 Pyrrolobenzodiazepine derivatives, compositions comprising the same and methods related thereto
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US Patent 7521541 Cysteine engineered antibodies and conjugates
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US Patent 7528126 Pyrrolobenzodiazepines
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US Patent 7557099 Pyrrolobenzodiazepines as key intermediates in the synthesis of dimeric cytotoxic pyrrolobenzodiazepines
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US Patent 7612062 Pyrrolobenzodiazepines
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US Patent 7704924 Library of compounds comprising pyrrolobenzodiazepine moieties
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US Patent 7723485 Cysteine engineered anti-MUC16 antibodies and antibody drug conjugates
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US Patent 7741319 11-hydroxy-5h-pyrrolo[2,1-c][1,4] benzodiazepin-5-one derivatives as key intermediates for the preparation of c2 substituted pyrrolobenzodiazepines
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US Patent 8034808 Therapeutic compositions containing at least one pyrrolobenzodiazepine derivative and fludarabine
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US Patent 8163736 Cytotoxic agents comprising new tomaymycin derivatives
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US Patent 8321774 Method for fail-safe transmission, safety switching device and control unit
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US Patent 8487092 Pyrrolobenzodiazepines
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US Patent 8501934 Pyrrolobenzodiazepines
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US Patent 8592576 Unsymmetrical pyrrolobenzodiazepine-dimers for treatment of proliferative diseases
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US Patent 8633185 Pyrrolobenzodiazepines
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US Patent 8637664 Alkyl 4- [4- (5-oxo-2,3,5, 11a-tetrahydo-5H-pyrrolo [2, 1-c] [1,4] benzodiazepine-8-yloxy)-butyrylamino]-1H-pyrrole-2-carboxylate derivatives and related compounds for the treatment of a proliferative disease
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US Patent 8697688 Pyrrolobenzodiazepines used to treat proliferative diseases
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US Patent 8829184 Intermediates useful for the synthesis of pyrrolobenzodiazepines
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US Patent 8940733 Unsymmetrical pyrrolobenzodiazepine-dimers for treatment of proliferative diseases
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US Patent 9102704 Synthesis method and intermediates useful in the preparation of pyrrolobenzodiazepines
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US Patent 9242013 Targeted pyrrolobenzodiazapine conjugates
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US Patent 9321774 Pyrrolobenzodiazepines
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US Patent 9376440 Pyrrolobenzodiazepines as antiproliferative agents
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US Patent 9387259 Pyrrolobenzodiazepines and targeted conjugates
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US Patent 9388187 Pyrrolobenzodiazepines
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US Patent 9399073 Pyrrolobenzodiazepines
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US Patent 9399641 Pyrrolobenzodiazepines as unsymmetrical dimeric PBD compounds for inclusion in targeted conjugates
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US Patent 9415117 Pyrrolobenzodiazepines and conjugates thereof
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US Patent 9464141 Anti-ETBR antibodies and immunoconjugates
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US Patent 9526798 Pyrrolobenzodiazepines and targeted conjugates
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US Patent 9562049 Pyrrolobenzodiazepines and conjugates thereof
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US Patent 9592240 Targeted pyrrolobenzodiazapine conjugates
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US Patent 9624227 Unsymmetrical pyrrolobenzodiazepine-dimers for treatment of proliferative diseases
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US Patent 9649390 Pyrrolobenzodiazepines and conjugates thereof
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US Patent 9707301 Pyrrolobenzodiazepines and targeted conjugates
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US Patent 9713647 Pyrrolobenzodiazepines and targeted conjugates
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US Patent 9732084 Pyrrolobenzodiazepines used to treat proliferative diseases
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US Patent 9745303 Synthesis and intermediates of pyrrolobenzodiazepine derivatives for conjugation
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US Patent 9889207 Pyrrolobenzodiazepines and conjugates thereof
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US Patent 9956298 Pyrrolobenzodiazepines and conjugates thereof
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US Patent 6884799 Non-cross-linking pyrrolo[2,1-c][1,4]benzodiazepines and process thereof
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US Patent 6909006 Cyclopropylindole derivatives
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US Patent 7049311 Pyrrolbenzodiazepines
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US Patent 7067511 Pyrrolobenzodiazepines
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Patent Primary Examiner
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Bruck Kifle
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CPC Code
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C07D 487/04
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A61K 47/6855
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A61K 47/6803
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A61K 47/65
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A61P 35/00
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