Patent attributes
Systems, eye-mountable devices, and methods that facilitate chronotherapeutic treatment of primary open-angle glaucoma are provided which enable therapeutic products to be delivered to the eye in a controlled manner only when desired. According to one embodiment, an eye-mountable device comprises a substrate having an eye-mounting surface for positioning on an eye of a patient, a sensor that obtains a plurality of measurements representative of a condition of the eye of the patient over a period of time, a therapeutic agent delivery assembly coupled, and a processor for executing a temporal model of a therapeutic agent delivery in communication with the sensor and the therapeutic agent delivery assembly. The processor receives the plurality of measurements and activates the therapeutic agent delivery assembly to administer a first amount of a drug to the eye of the patient based on the temporal model associated with the plurality of measurements.