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US Patent 12128092 Lyophilized factor IX formulations

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Is a

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Patent attributes

Patent Jurisdiction

United States Patent and Trademark Office

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Patent Number

Patent Inventor Names

Brandon W. Leveille0

Brian M. Thome0

Cherie Parkhurst-Lang0

Date of Patent

October 29, 2024

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Patent Application Number

169951730

Date Filed

August 17, 2020

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Patent Citations

US Patent 7790415 Enhancing the circulating half-life of antibody-based fusion proteins

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US Patent 7862820 Immunoglobulin chimeric monomer-dimer hybrids

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US Patent 8015841 Cryogenic refrigeration system for lyophilization

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US Patent 8048848 Long-acting interferons and derivatives thereof and methods thereof

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US Patent 8367805 Fc variants with altered binding to FcRn

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US Patent 10588949 Factor IX polypeptide formulations

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US Patent 8563521 Biological active proteins having increased in vivo and/or in vitro stability

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US Patent 10772942 Lyophilized factor IX formulations

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...

Patent Primary Examiner

Michael Szperka

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Patent abstract

The present invention provides, among other things, pre-lyophilization formulations, reconstituted formulations, and lyophilate powder compositions comprising a Factor IX (FIX) polypeptide. The present invention also provides lyophilization methods for producing lyophilate powder comprising a FIX polypeptide.

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