Patent 6861254 was granted and assigned to Massachusetts Institute of Technology on March, 2005 by the United States Patent and Trademark Office.
Disclosed are novel isolated nucleic acids and substantially pure protein preparations for naturally occurring and synthetic or chimeric heparan sulfate D-glicosaminyl 3-O-sulfo-transferases (3-OSTs). Also disclosed are uses for these genes and proteins, including uses for the modification and sequencing of glycosaminoglycans.