US Patent 7005131 Protective antigen of Epstein Barr Virus
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Patent abstract
The present invention relates to the identification of a subunit vaccine to prevent or treat infection of Epstein Barr Virus. In particular, EBNA-1 was identified as a vaccine antigen. In a specific embodiment, a purified protein corresponding to EBNA-1 elicited a strong CD4+ T cell response. The responsive CD4+ T cell are primarily TH1 in function. EBNA-1 is an attractive candidate for a protective vaccine against EBV, and for immunotherapy of EBV infection and neoplasms, particularly with dendritic cells charged with EBNA-1.
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Patent Inventor Names
Christian Muenz0
Ralph M. Steinman0
Date of Patent
February 28, 2006
0Patent Application Number
100493160
Date Filed
August 10, 2000
0Patent Primary Examiner
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US Patent 7005131 Protective antigen of Epstein Barr Virus
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