Is a
Patent attributes
Current Assignee
Patent Jurisdiction
Patent Number
Patent Inventor Names
George D. Yancopoulos0
Nicholas J. Papadopoulos0
Samuel Davis0
Date of Patent
July 4, 2006
0Patent Application Number
100098520
Date Filed
May 23, 2000
0Patent Citations Received
0
...
Patent Primary Examiner
Patent abstract
Modified chimeric polypeptides with improved pharmacokinetics are disclosed. Specifically, modified chimeric Flt1 receptor polypeptides that have been modified in such a way as to improve their pharmacokinetic profile are disclosed. Also disclosed are methods of making and using the modified polypeptides including but not limited to using the modified polypeptides to decrease or inhibit plasma leakage and/or vascular permeability in a mammal.
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