Is a
Patent attributes
Patent Jurisdiction
Patent Number
Patent Inventor Names
Brian K. Kaspar0
Fred H. Gage0
Date of Patent
September 5, 2006
0Patent Application Number
102375670
Date Filed
September 5, 2002
0Patent Citations Received
Patent Primary Examiner
Patent abstract
Methods are disclosed for delivering a heterologous gene to a cell body of a neuron by contacting a muscle tissue innervated by the neuron with a viral vector comprising a heterologous gene, wherein the viral vector enters said neuron and is retrogradely moved to the cell body. Additionally, methods for expressing secreted proteins from a nerve cell body as well as methods for treating neurodegenerative disorders such as amyotrophic lateral sclerosis are described.
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