Is a
Patent attributes
Current Assignee
Patent Jurisdiction
Patent Number
Patent Inventor Names
Stephen B. H. Kent0
Paolo Botti0
Shiah-yun Chen0
Sonya Cressman0
Christie L. Hunter0
Donald W. Low0
Gerd G. Kochendoerfer0
James A. Bradburne0
...
Date of Patent
October 10, 2006
0Patent Application Number
103323850
Date Filed
July 12, 2001
0Patent Primary Examiner
Patent abstract
The present invention relates to methods and compositions for modifying peptides, polypeptides and proteins with polymers, especially glyco-mimetic polymers, so as to improve their biological activity or pharmacokinetic properties. The invention further provides methods and uses for such polymer-modified peptides, polypeptides and proteins. The invention is particularly suitable for use in the synthesis of polymer-modified synthetic bioactive proteins (FIG. 1D), and of pharmaceutical compositions that contain such proteins.
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