US Patent 7118737 Polymer-modified synthetic proteins

Patent 7118737 was granted and assigned to Amylin Pharmaceuticals on October, 2006 by the United States Patent and Trademark Office.

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Patent Inventor Names

Christie L. Hunter0

Donald W. Low0

Gerd G. Kochendoerfer0

James A. Bradburne0

Jill G. Wilken0

Paolo Botti0

Shiah-yun Chen0

Sonya Cressman0

Stephen B. H. Kent0

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Patent abstract

The present invention relates to methods and compositions for modifying peptides, polypeptides and proteins with polymers, especially glyco-mimetic polymers, so as to improve their biological activity or pharmacokinetic properties. The invention further provides methods and uses for such polymer-modified peptides, polypeptides and proteins. The invention is particularly suitable for use in the synthesis of polymer-modified synthetic bioactive proteins (FIG. 1D), and of pharmaceutical compositions that contain such proteins.

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Official Website

https://pdfpiw.uspto.gov/.piw?Docid=071187370

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