Is a
Patent attributes
Current Assignee
Patent Jurisdiction
Patent Number
Patent Inventor Names
Robert D. Bremel0
Anthony W. S. Chan0
Jane C. Burns0
Date of Patent
November 21, 2006
0Patent Application Number
099078590
Date Filed
July 18, 2001
0Patent Primary Examiner
Patent abstract
The present invention provides improved methods and compositions for the generation of transgenic non-human animals. The present invention permits the introduction of exogenous nucleic acid sequences into the genome of unfertilized eggs (e.g., pre-maturation oocytes and pre-fertilization oocytes) by microinjection of infectious retrovirus into the perivitelline space of the egg. The methods of the present invention provide an increased efficiency of production of transgenic animals with a reduced rate of generating animals which are mosaic for the presence of the transgene.
Timeline
No Timeline data yet.
Further Resources
No Further Resources data yet.
