Is a
Patent attributes
Current Assignee
Patent Jurisdiction
Patent Number
Patent Inventor Names
Michael B. Kastan0
Christopher Bakkenist0
Date of Patent
January 9, 2007
0Patent Application Number
110764050
Date Filed
March 9, 2005
0Patent Primary Examiner
Patent abstract
The present invention provides methods for detecting activation of ATM kinase, DNA damage, and DNA damaging agents. Further provided are antibodies which specifically recognize the phosphorylation state of Ataxia Telangiectasia-Mutated (ATM) kinase. Methods of identifying agents which modulate the activation and activity of ATM kinase are also provided.
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