US Patent 7205386 Truncated CD200
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Patent Inventor Names
Reginald M. Gorczynski0
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Patent abstract
A truncated form of the full-length, immunosuppression-inducing molecule, CD200, CD200tr, was expressed in CHO cells and the transduced cells used to produce mAbs to CD200tr. These mAbs detect simultaneous expression of full-length CD200 and CD200tr in LPS-stimulated dendritic cells (DCs). Moreover, CHO cells and DCs expressing CD200tr as well as soluble CD200tr are able to inhibit suppression of mixed leucocyte reactions in vitro which follows addition of the soluble form of CD200 (CD200:Fc) in culture, demonstrating that CD200tr is a physiological antagonist of CD200.
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US Patent 07205386 Truncated CD200 US Patent 7205386 Truncated CD200
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Patent Number
072053860
Patent Number
72053860
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Patent Jurisdiction
Patent Number
072053860
Date of Patent
April 17, 2007
0Patent Application Number
104165100
Date Filed
November 22, 2001
0Official Website
Patent Primary Examiner
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US Patent 07205386 Truncated CD200
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Is a
Patent jurisdiction
Patent number
07205386
Date of patent
April 17, 2007
Patent application number
10416510
Date Filed
November 22, 2001
Patent primary examiner
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