Patent 7226990 was granted and assigned to Novo Nordisk on June, 2007 by the United States Patent and Trademark Office.
The present invention relates to novel derivatives of exendin-4 or exendin-4 fragments, wherein the derivatives have a lipophilic substituent attached, optionally via a spacer, to an amino acid residue, which is not the N-terminal or C-terminal amino acid residue of the derivative.