US Patent 7297476 Method of monitoring HIV assembly and maturation
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Patent abstract
The present invention provides methods to characterize the structure, stability, and intersubunit interfaces between the matrix, capsid, and nucleocapsid domains of the Gag polyprotein during HIV capsid assembly and maturation. A method of screening for compounds that promote or inhibit viral assembly and maturation is disclosed. A novel mass spectrometry based approach to measure hydrogen/deuterium exchange profiles is also disclosed. Quantitative data resulted from these studies may lead to well defined capsid assembly assays that can be adapted for rapid antiviral drug screening.
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US Patent 07297476 Method of monitoring HIV assembly and maturation US Patent 7297476 Method of monitoring HIV assembly and maturation
Infobox
Patent Number
0729747600
Patent Number
729747600
Edits on 22 Apr, 2023
Golden AI
Infobox
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Patent Jurisdiction
Patent Number
072974760
Date of Patent
November 20, 2007
0Patent Application Number
098002400
Date Filed
March 6, 2001
0Official Website
Patent Primary Examiner
Edits on 25 Sep, 2022
Golden AI
Infobox
Is a
Patent Jurisdiction
Patent Number
072974760
Date of Patent
November 20, 2007
0Patent Application Number
098002400
Date Filed
March 6, 2001
0Official Website
Patent Primary Examiner
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US Patent 07297476 Method of monitoring HIV assembly and maturation
Infobox
Is a
Patent jurisdiction
Patent number
07297476
Date of patent
November 20, 2007
Patent application number
09800240
Date Filed
March 6, 2001
Patent primary examiner
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