US Patent 7312047 Screening assay for improvement of epithelial barrier function
Patent 7312047 was granted and assigned to University of Southampton on December, 2007 by the United States Patent and Trademark Office.
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Patent Inventor Names
Donna Elizabeth Davies0
Sarah M. Puddicombe0
Stephen Holgate0
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Patent abstract
The present invention relates to the use of an air-liquid interface culture model using asthmatic bronchial epithelial cells, which exhibit impaired epithelial barrier function. It is proposed to use asthmatic epithelial cultures, in the absence of added Th2 or proinflammatory cytokines such as IL-13, as an in vitro model to screen for agents that can act to improve impaired asthmatic epithelial barrier function. Such agents may have therapeutic utility in asthma patients.
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US Patent 07312047 Screening assay for improvement of epithelial barrier function US Patent 7312047 Screening assay for improvement of epithelial barrier function
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Patent Number
073120470
Patent Number
73120470
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Is a
Current Assignee
Patent Jurisdiction
Patent Number
073120470
Date of Patent
December 25, 2007
0Patent Application Number
111353390
Date Filed
May 24, 2005
0Official Website
Patent Primary Examiner
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US Patent 07312047 Screening assay for improvement of epithelial barrier function
Infobox
Is a
Current assignee
Patent jurisdiction
Patent number
07312047
Date of patent
December 25, 2007
Patent application number
11135339
Date Filed
May 24, 2005
Patent primary examiner
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