Is a
Patent attributes
Patent Jurisdiction
Patent Number
Patent Inventor Names
Kenneth Brooks Low0
David Bermudes0
Date of Patent
April 8, 2008
0Patent Application Number
110645330
Date Filed
February 23, 2005
0Patent Citations Received
Patent Primary Examiner
Patent abstract
The present invention is directed to mutant Salmonella sp. having a genetically modified msbB gene in which the mutant Salmonella is capable of targeting solid tumors. The invention is also directed to Salmonella sp. containing a genetically modified msbB gene as well as an genetic modification in a biosynthetic pathway gene such as the purl gene. The present invention further relates to the therapeutic use of the mutant Salmonella for growth inhibition and/or reduction in volume of solid tumors.
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