US Patent 7521473 Inhibitors of protein tyrosine phosphatase 1B
Patent 7521473 was granted and assigned to Wyeth on April, 2009 by the United States Patent and Trademark Office.
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Patent Inventor Names
Bruce C. Follows0
David V. Erbe0
Douglas P. Wilson0
Jinbo Lee0
Jun-Jun Wu0
Kenneth W. Foreman0
Michael J. Smith0
Steve Y. Tam0
Steven J. Kirincich0
Weixin Xu0
Yan-Ling Zhang0
Zhao-Kui Wan0
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Patent abstract
Protein tyrosine phosphatases (PTPases) such as PTP1B can play a role in regulating a wide variety of cellular responses such as insulin signaling. Substituted thiophene compounds such as, for example, 2-carboxyl, 3-carboxymethoxy, 5-aryl substituted thiophenes, can inhibit PTP1B and thereby induce greater insulin sensitivity. Accordingly, PTP1B inhibition can provide an alternate treatment for PTPase-mediated disorders such as diabetes.
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US Patent 07521473 Inhibitors of protein tyrosine phosphatase 1B US Patent 7521473 Inhibitors of protein tyrosine phosphatase 1B
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Patent Number
075214730
Patent Number
75214730
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Is a
Current Assignee
Patent Jurisdiction
Patent Number
075214730
Date of Patent
April 21, 2009
0Patent Application Number
110634750
Date Filed
February 23, 2005
0Official Website
Patent Primary Examiner
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US Patent 07521473 Inhibitors of protein tyrosine phosphatase 1B
Infobox
Is a
Current assignee
Patent jurisdiction
Patent number
07521473
Date of patent
April 21, 2009
Patent application number
11063475
Date Filed
February 23, 2005
Patent primary examiner
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