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US Patent 7595179 Recombinant reverse transcriptases

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Is a

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Patent attributes

Patent Jurisdiction

United States Patent and Trademark Office

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Patent Number

Patent Inventor Names

Robert A. Setterquist0

Gary J. Latham0

Liangjing Chen0

Date of Patent

September 29, 2009

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Patent Application Number

108274980

Date Filed

April 19, 2004

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Patent Citations Received

US Patent 12084663 Incorporation of unnatural amino acids into proteins using base editing

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US Patent 11920181 Nuclease profiling system

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US Patent 11932884 High efficiency base editors comprising Gam

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US Patent 11999947 Adenosine nucleobase editors and uses thereof

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US Patent 12006520 Evaluation and improvement of nuclease cleavage specificity

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US Patent 12065645 Reverse transcriptases and uses thereof

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US Patent 11661590 Programmable CAS9-recombinase fusion proteins and uses thereof

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Patent Primary Examiner

Richard G Hutson

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Patent abstract

The present invention relates to a gene that encodes a hyperactive reverse transcriptase having DNA polymerase activity and substantially reduced RNase H activity, vectors containing the gene and host cells transformed with the invention. The present invention also includes a method of producing the hyperactive reverse transcriptase, producing cDNA from mRNA using the reverse transcriptase of the invention, kits and assay templates made using the hyperactive reverse transcriptase.

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