Is a
Patent attributes
Patent Jurisdiction
Patent Number
Patent Inventor Names
Audra Lynn Stinchcomb0
Mohamed Omer Hamad0
Peter A. Crooks0
Date of Patent
July 20, 2010
0Patent Application Number
108974280
Date Filed
July 23, 2004
0Patent Primary Examiner
Patent abstract
The invention is directed to forming duplex prodrugs that provide significant increase in the transdermal flux of drugs across human skin. The prodrugs are prepared by reacting a drug that can form an ester moiety with phosgene to form a carbonate. The drug can be an opiate or an opiate antagonist. When in contact with human skin, the duplex drug is biotransformed by enzymes or by hydrolysis into two drug molecules.
Timeline
No Timeline data yet.
Further Resources
No Further Resources data yet.
