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US Patent 7799565 Lipid encapsulated interfering RNA

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Patent attributes

Patent Jurisdiction

United States Patent and Trademark Office

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Patent Number

Patent Inventor Names

James Heyes0

Lorne R. Palmer0

Ian MacLachlan0

Date of Patent

September 21, 2010

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Patent Application Number

111481520

Date Filed

June 7, 2005

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Patent Citations Received

US Patent 12129467 Non-liposomal systems for nucleic acid delivery

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US Patent 12060381 Methods for purification of messenger RNA

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US Patent 12064479 Lipid nanoparticles for delivery of nucleic acids and methods of use thereof

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US Patent 12065396 Lipids for use in lipid nanoparticle formulations

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US Patent 12077725 Ionizable cationic lipids

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US Patent 12084702 Methods for purification of messenger RNA

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US Patent 12129223 Lipids for use in lipid nanoparticle formulations

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US Patent 11707482 Delivery of RNA to trigger multiple immune pathways

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Patent Primary Examiner

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Patent abstract

The present invention provides lipid-based formulations for delivering, e.g., introducing, nucleic acid-lipid particles comprising an interference RNA molecule to a cell, and assays for optimizing the delivery efficiency of such lipid-based formulations.

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