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US Patent 7838658 siRNA silencing of filovirus gene expression

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Patent
Patent
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Patent attributes

Patent Jurisdiction
United States Patent and Trademark Office
United States Patent and Trademark Office
0
Patent Number
78386580
Patent Inventor Names
Thomas W. Geisbert0
Vandana Sood0
Elliott Kagan0
Ian MacLachlan0
Lisa E. Hensley0
Date of Patent
November 23, 2010
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Patent Application Number
115843410
Date Filed
October 20, 2006
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Patent Citations Received
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US Patent 12129467 Non-liposomal systems for nucleic acid delivery
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US Patent 11840711 Type VI CRISPR orthologs and systems
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US Patent 11865190 Compositions and systems comprising transfection-competent vesicles free of organic-solvents and detergents and methods related thereto
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US Patent 11903974 Methods and compositions relating to chondrisomes from cultured cells
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US Patent 11903975 Methods and compositions relating to chondrisomes from blood products
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US Patent 11980673 Compositions and systems comprising transfection-competent vesicles free of organic-solvents and detergents and methods related thereto
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US Patent 12016929 Lipid formulations for delivery of therapeutic agents
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US Patent 12064479 Lipid nanoparticles for delivery of nucleic acids and methods of use thereof
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...
Patent Primary Examiner
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Kimberly Chong
0
Patent abstract

The present invention provides siRNA molecules that target Filovirus gene expression and methods of using such siRNA molecules to silence Filovirus gene expression. The present invention also provides nucleic acid-lipid particles that target Filovirus gene expression comprising an siRNA that silences Filovirus gene expression, a cationic lipid, and a non-cationic lipid.

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