US Patent 7869958 Structure-based modulators of B1 G-protein coupled receptors
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Patent abstract
The present invention relates to a method for identifying modulators of B1 G-protein coupled receptors. The present invention also relates to a method for identifying an antagonist or agonist of the corticotropin-releasing factor receptor 2 (CRFR2). The present invention also relates to a method for improving antagonists or agonists of CRFR2. The present invention also relates to the three-dimensional structure of CRFR2 as representative of the B1 GPCR subfamily and its use as a basis for rational drug design of antagonist or agonists of B1 GPCRs.
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Patent Inventor Names
Grace Christy Rani Royappa0
Jean E. Rivier0
Marilyn H. Perrin0
Roland Riek0
Wylie W. Vale, Jr.0
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US Patent 07869958 Structure-based modulators of B1 G-protein coupled receptors US Patent 7869958 Structure-based modulators of B1 G-protein coupled receptors
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Patent Number
078699580
Patent Number
78699580
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Patent Jurisdiction
Patent Number
078699580
Date of Patent
January 11, 2011
0Patent Application Number
111998210
Date Filed
August 9, 2005
0Official Website
Patent Primary Examiner
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US Patent 07869958 Structure-based modulators of B1 G-protein coupled receptors
Infobox
Is a
Patent jurisdiction
Patent number
07869958
Date of patent
January 11, 2011
Patent application number
11199821
Date Filed
August 9, 2005
Patent primary examiner
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