Is a
Patent attributes
Patent Jurisdiction
Patent Number
Patent Inventor Names
Andre Trouet0
Vincent Dubois0
Alexandre Passioukov0
Date of Patent
February 22, 2011
0Patent Application Number
121575750
Date Filed
June 11, 2008
0Patent Citations Received
Patent Primary Examiner
Patent abstract
The product of the invention is a modified form of a therapeutic agent and comprises a therapeutic agent, an oligopeptide having a plasmin peptide substrate of 2-4 amino acids and mono- or di-peptide linkage, a stabilizing group and, optionally, a linker group. The prodrug is cleavable by plasmin. Also disclosed are methods of making and using the prodrug compounds.
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