Is a
Patent attributes
Patent Jurisdiction
Patent Number
Patent Inventor Names
Robert S. Langer0
Yi Lin Cao0
Charles A. Vacanti0
Joseph P. Vacanti0
Joseph Upton0
Keith Paige0
Date of Patent
March 29, 2011
Patent Application Number
11351127
Date Filed
February 9, 2006
Patent Citations Received
Patent Primary Examiner
Patent abstract
Connective tissue, including neo-tendons and ligaments, has been constructed using biodegradable synthetic scaffolds seeded with tenocytes. The scaffolds are preferably formed from biodegradable fibers formed of a polymer such as polyglycolic acid-polylactic acid copolymers, and seeded with cells isolated from autologous tendon or ligament by means of enzymatic digestion or direct seeding into tissue culture dishes from explants. The cell polymer constructs are then surgically transplanted to replace missing segments of functioning tendon or ligament.
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