US Patent 7989169 Selective amplification of methylated nucleic acids
Patent 7989169 was granted and assigned to Roche Molecular Systems on August, 2011 by the United States Patent and Trademark Office.
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Patent abstract
The invention is related to a method for amplifying a methylated target nucleic acid in a sample while avoiding amplification of a non-methylated target nucleic acid by inactivating it. This is accomplished by a restriction enzyme digest after bisulfite treatment of the target nucleic acid. The invention is further related to the use of a restriction enzyme to avoid amplification of a non-methylated target nucleic acid while amplifying a methylated target nucleic acid in a sample and kits for performing the methods according to the invention.
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Patent Inventor Names
Christine Markert-Hahn0
Frank Bergmann0
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US Patent 07989169 Selective amplification of methylated nucleic acids US Patent 7989169 Selective amplification of methylated nucleic acids
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Patent Number
07989169
Patent Number
7989169
Edits on 8 Dec, 2021
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US Patent 07989169 Selective amplification of methylated nucleic acids
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Is a
Current assignee
Patent jurisdiction
Patent number
07989169
Date of patent
August 2, 2011
Patent application number
11658569
Date Filed
September 2, 2005
Patent primary examiner
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