Patent 8053415 was granted and assigned to Washington University in St. Louis on November, 2011 by the United States Patent and Trademark Office.
The present invention provides compounds that have motifs that target the compounds to cells that express integrins. In particular, the compounds have peptides with one or more RD motifs conjugated to an agent selected from an imaging agent and a targeting agent. The compounds may be used to detect, monitor and treat a variety of disorders mediated by integrins.