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US Patent 8084032 Purification method which prevents denaturation of an antibody

Patent 8084032 was granted and assigned to AJINOMOTO CO., INC. on December, 2011 by the United States Patent and Trademark Office.

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Patent attributes

Current Assignee

AJINOMOTO CO., INC.

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Patent Jurisdiction

United States Patent and Trademark Office

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Patent Number

Patent Inventor Names

Daisuke Ejima1

Ryosuke Yumioka1

Tsutomu Arakawa1

Date of Patent

December 27, 2011

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Patent Application Number

110300881

Date Filed

January 7, 2005

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Patent Citations Received

US Patent 12134633 Separation matrix

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US Patent 11753438 Method of cleaning and/or sanitizing a separation matrix

US Patent 11850535 Methods for quantitating individual antibodies from a mixture

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US Patent 11884698 Systems and methods for preparing a polypeptide from a mixture

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US Patent 12070502 Process for reducing subvisible particles in a pharmaceutical formulation

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US Patent 12091433 Non-antibody high-affinity-based sample preparation, sorbent, devices and methods

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US Patent 11667671 Separation method

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Patent Primary Examiner

1

Patent abstract

The present invention provides a method of purifying an antibody by protein A affinity chromatography. More specifically, the present invention provides a technique relating to an elution buffer solution which provides a good antibody recovery rate without denaturation.

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