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US Patent 8101720 Immunoglobulin insertions, deletions and substitutions

Patent 8101720 was granted and assigned to Xencor on January, 2012 by the United States Patent and Trademark Office.

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Patent abstract

An Fc variant of a parent Fc polypeptide, wherein said Fc variant exhibits altered binding to one or more FcγRs, wherein said Fc variant comprises at least one amino acid insertion in the Fc region of said parent Fc polypeptide.

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