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US Patent 8187855 Large-scale production of soluble hyaluronidase

Patent 8187855 was granted and assigned to Halozyme, Inc. on May, 2012 by the United States Patent and Trademark Office.

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US Patent 12123035 PH20 polypeptide variants, formulations and uses thereof
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US Patent 12110520 PH20 polypeptide variants, formulations and uses thereof
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US Patent 12104185 PH20 polypeptide variants, formulations and uses thereof
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US Patent 12104184 PH20 polypeptide variants, formulations and uses thereof
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US Patent 12091692 PH20 polypeptide variants, formulations and uses thereof
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US Patent 12060590 PH20 polypeptide variants, formulations and uses thereof
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US Patent 12018298 PH20 polypeptide variants, formulations and uses thereof
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US Patent 11952600 PH20 polypeptide variants, formulations and uses thereof
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Patent abstract

Provided are methods for preparing large-scale preparations of soluble hyaluronidases. The methods employ cells that contain a plurality of active copies of nucleic acid encoding the soluble hyaluronidase and a plurality of feedings and temperature changes, whereby the encoded soluble hyaluronidase is secreted into the cell culture medium.

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Patent Inventor Names
David Baker0
Louis H. Bookbinder0
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US Patent 11661456 Sialylated glycoproteins
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US Patent 08187855 Large-scale production of soluble hyaluronidase US Patent 8187855 Large-scale production of soluble hyaluronidase

Infobox
Patent Number
081878550
Patent Number
81878550
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Infobox
Is a
Patent
Patent
0
Current Assignee
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Halozyme, Inc.
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Patent Jurisdiction
United States Patent and Trademark Office
United States Patent and Trademark Office
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Patent Number
081878550
Date of Patent
May 29, 2012
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Patent Application Number
127358680
Date Filed
March 6, 2009
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Patent Primary Examiner
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Herbert J. Lilling
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 US Patent 08187855 Large-scale production of soluble hyaluronidase

Infobox
Is a
Patent
Patent
Current assignee
‌
Halozyme, Inc.
Patent jurisdiction
United States Patent and Trademark Office
United States Patent and Trademark Office
Patent number
08187855
Date of patent
May 29, 2012
Patent application number
12735868
Date Filed
March 6, 2009
Patent primary examiner
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Herbert J. Lilling

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