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US Patent 8188231 Optimized FC variants

Patent 8188231 was granted and assigned to Xencor on May, 2012 by the United States Patent and Trademark Office.

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Patent attributes

Current Assignee

Patent Jurisdiction

United States Patent and Trademark Office

Patent Number

Date of Patent

May 29, 2012

Patent Application Number

11124620

Date Filed

May 5, 2005

Patent Citations Received

US Patent 12122840 Method of modifying isoelectric point of antibody via amino acid substitution in CDR

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US Patent 11919935 Ultra-long acting insulin-Fc fusion proteins and methods of use

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US Patent 12084513 Anti-C1S antibodies and methods of use

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US Patent 12116414 Method of modifying isoelectric point of antibody via amino acid substitution in CDR

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US Patent 11667689 Insulin-Fc fusion proteins and methods of use to treat cancer

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US Patent 11673934 Ultra-long acting insulin-Fc fusion proteins and methods of use

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US Patent 11673945 Bispecific antigen binding proteins

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US Patent 11773151 Ultra-long acting insulin-Fc fusion proteins and methods of use

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Patent Primary Examiner

Patent abstract

The present invention relates to optimized Fc variants, methods for their generation, Fc polypeptides comprising optimized Fc variants, and methods for using optimized Fc variants.

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