Is a
Patent attributes
Patent Jurisdiction
Patent Number
Patent Inventor Names
Gregory Verdine0
Loren D. Walensky0
Stanley J. Korsmeyer0
Date of Patent
June 12, 2012
0Patent Application Number
121826730
Date Filed
July 30, 2008
0Patent Citations Received
Patent Primary Examiner
Patent abstract
Novel polypeptides and methods of making and using the same are described herein. The polypeptides include cross-linking (“hydrocarbon stapling”) moieties to provide a tether between two amino acid moieties, which constrains the secondary structure of the polypeptide. The polypeptides described herein can be used to treat diseases characterized by excessive or inadequate cellular death.
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