Is a
Patent attributes
Current Assignee
Patent Jurisdiction
Patent Number
Patent Inventor Names
Brock Binkowski0
Keith V. Wood0
Lance P. Encell0
Mary Hall0
Matthew B. Robers0
Michael R. Slater0
Monika G. Wood0
Date of Patent
March 11, 2014
0Patent Application Number
132879860
Date Filed
November 2, 2011
0Patent Citations Received
Patent Primary Examiner
Patent abstract
An isolated polynucleotide encoding a modified luciferase polypeptide and substrates. The OgLuc variant polypeptide has at least 60% amino acid sequence identity to SEQ ID NO: 1 and at least one amino acid substitution at a position corresponding to an amino acid in SEQ ID NO: 1. The OgLuc variant polypeptide has at least one of enhanced luminescence, enhanced signal stability, and enhanced protein stability relative to the corresponding polypeptide of the wild-type Oplophorus luciferase.
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