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US Patent 8697854 High affinity T cell receptor and use thereof

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US Patent 11994512 Single-cell genomic methods to generate ex vivo cell systems that recapitulate in vivo biology with improved fidelity

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US Patent 11981922 Methods and compositions for the modulation of cell interactions and signaling in the tumor microenvironment

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US Patent 11963966 Compositions and methods for treating ovarian tumors

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US Patent 11957695 Methods and compositions targeting glucocorticoid signaling for modulating immune responses

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US Patent 11939637 Molecular biomarkers for cancer immunotherapy

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US Patent 11913075 Methods and compositions for detecting and modulating an immunotherapy resistance gene signature in cancer

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US Patent 11884717 Method of treating autoimmune disease with lymphocyte antigen CD5-like (CD5L) protein

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US Patent 11885815 Reducing junction epitope presentation for neoantigens

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US Patent 11865168 Compositions and methods for treating bacterial infections

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US Patent 11834718 Compositions and methods for diagnosing, evaluating and treating cancer by means of the DNA methylation status

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Patent abstract

The present invention is directed to a high affinity T cell receptor (TCR) against a tumor-associated antigen, an isolated nucleic acid molecule encoding same, a T cell expressing said TCR, and a pharmaceutical composition for use in the treatment of diseases involving malignant cells expressing said tumor-associated antigen.

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Patent Inventor Names

Bernhard Frankenberger0

Dolores Schendel0

Susanne Wilde0

Wolfgang Uckert0

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US Patent 11752172 Natural killer (NK) cells expressing an antigen-specific functional T cell receptor (TCR) complex, methods for production thereof, and methods for therapeutic use thereof

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Official Website

https://pdfpiw.uspto.gov/.piw?Docid=086978540

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US Patent 11667695 Antibodies and processes for preparing the same

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US Patent 08697854 High affinity T cell receptor and use thereof US Patent 8697854 High affinity T cell receptor and use thereof

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Patent Number

086978540

Patent Number

86978540

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Is a

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Patent Jurisdiction

United States Patent and Trademark Office

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Patent Number

086978540

Date of Patent

April 15, 2014

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Patent Application Number

131306650

Date Filed

November 24, 2009

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Official Website

https://pdfpiw.uspto.gov/.piw?Docid=086978540

Patent Primary Examiner

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Website URL

https://pdfpiw.uspto.gov/.piw?Docid=08697854

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