Is a
Patent attributes
Patent Jurisdiction
Patent Number
Patent Inventor Names
Daniel J. O'Sullivan0
Ju-Hoon Lee0
Date of Patent
January 13, 2015
0Patent Application Number
131000050
Date Filed
May 3, 2011
0Patent Citations Received
Patent Primary Examiner
Patent abstract
The present invention provides isolated lantibiotics that inhibit. Gram negative and Gram positive microbes. The antibiotic includes an amino acid sequence, wherein the amino acid sequence of the compound and the amino acid sequence of SEQ ID NO:21 or SEQ ID NO:22 have at least 80% identity. The lantibiotics have the characteristic of inhibiting growth of a Gram negative microbe in conditions that do not damage the outer membrane of the Gram negative microbe. The present invention also provides methods for making and using the lantibiotics.
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