Is a
Patent attributes
Current Assignee
0
Patent Jurisdiction
Patent Number
Patent Inventor Names
Sriharsa Pradhan0
Yu Zheng0
Christopher Noren0
Devora Cohen-Karni0
Elisabeth A. Raleigh0
Geoffrey Wilson0
Hang-Gyeong Chin0
Jurate Bitinaite0
...
Date of Patent
May 19, 2015
0Patent Application Number
133922860
Date Filed
August 25, 2010
0Patent Citations Received
Patent Primary Examiner
Patent abstract
Methods and compositions are described for detecting hydroxymethylated nucleotides (hmNs) in a polynucleotide preparation with a view to mapping the location of hmNs in a genome, quantifying the occurrence of hmNs at selected loci and correlating the occurrence of hmNs with gene expression and phenotypic traits. Embodiments describe the use of modifying enzymes together with site-specific endonucleases to detect the hmNs.
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