Is a
Patent attributes
Current Assignee
Patent Jurisdiction
Patent Number
Date of Patent
July 21, 2015
0Patent Application Number
131324230
Date Filed
December 3, 2009
0Patent Citations Received
Patent Primary Examiner
Patent abstract
The present invention relates to positions in the constant region of antibodies, in particular the CH3 region of IgG4, which affect the strength of CH3-CH3 interactions. Mutations that either stabilize or destabilize this interaction are disclosed.
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