Is a
Patent attributes
Patent Jurisdiction
Patent Number
Patent Inventor Names
Fangting Wu0
Date of Patent
January 12, 2016
Patent Application Number
14211858
Date Filed
March 14, 2014
Patent Citations Received
0
0
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Patent Primary Examiner
Patent abstract
The invention relates to engineered CRISPR/Cas9 systems for genomic modification in mammalian cells. The present specification describes the design and testing of a polynucleotide encoding the Streptococcus pyogenes (S. pyogenes) Cas9 protein, where the nucleotide sequence has been optimized for expression in mammalian cells. The specification also describes all-in-one systems for RNA-guided genome engineering in mammalian cells, including human cells.
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