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US Patent 9289477 Tolerogenic synthetic nanocarriers to reduce cytotoxic T lymphocyte responses

Patent 9289477 was granted and assigned to SELECTA BIOSCIENCES INC on March, 2016 by the United States Patent and Trademark Office.

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Patent abstract

Disclosed are synthetic nanocarrier compositions, and related methods, comprising MHC Class I-restricted and/or MHC Class II-restricted epitopes associated with undesired CD8+ T cell responses and immunosuppressants that provide tolerogenic immune responses against antigens that comprise the epitopes.

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