Is a
Patent attributes
Patent Jurisdiction
Patent Number
Patent Inventor Names
Richard Jude Samulski0
Matthew Louis Hirsch0
Date of Patent
September 20, 2016
0Patent Application Number
142119270
Date Filed
March 14, 2014
0Patent Citations Received
...
Patent Primary Examiner
Patent abstract
This invention relates to synthetic adeno-associated virus (AAV) inverted terminal repeats (ITRs) that exhibit altered activities compared to a naturally occurring AAV ITR and methods of using the same for delivery of nucleic acids to a cell or a subject. The synthetic ITRs provide a larger packaging capacity and the ability to manipulate activities such as transduction efficiency, cellular response to transduction, and transcription.
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