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US Patent 9464088 Piperidin-4-yl azetidine derivatives as JAK1 inhibitors

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Is a

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Patent attributes

Patent Jurisdiction

United States Patent and Trademark Office

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Patent Number

Patent Inventor Names

Chu-Biao Xue0

Hui-Yin Li0

Qun Li0

Taisheng Huang0

Date of Patent

October 11, 2016

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Patent Application Number

142891210

Date Filed

May 28, 2014

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Patent Citations Received

US Patent 11833155 Combination therapy for treatment of myeloproliferative neoplasms

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US Patent 12071439 Process and intermediates for preparing a JAK inhibitor

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US Patent 11857563 Inhibition of expansion and function of pathogenic age-associated B cells and use for the prevention and treatment of autoimmune disease

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US Patent 11744832 Heteroaryl substituted pyrrolo[2,3-b]pyridines and pyrrolo[2,3-b]pyrimidines as Janus kinase inhibitors

US Patent 11905292 Process and intermediates for preparing a JAK inhibitor

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US Patent 11992490 Use of JAK1 inhibitors for the treatment of cutaneous lupus erythematosus and Lichen planus (LP)

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Patent Primary Examiner

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Patent abstract

The present invention provides piperidin-4-yl azetidine derivatives, as well as their compositions and methods of use, that modulate the activity of Janus kinase 1 (JAK1) and are useful in the treatment of diseases related to the activity of JAK1 including, for example, inflammatory disorders, autoimmune disorders, cancer, and other diseases.

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