Is a
Patent attributes
Patent Jurisdiction
Patent Number
Patent Inventor Names
Daniel R. Goldberg0
Stéphane De Lombaert0
Kenneth Brameld0
Andrew Scribner0
Eric Brian Sjogren0
Date of Patent
December 6, 2016
Patent Application Number
14841868
Date Filed
September 1, 2015
Patent Citations Received
Patent Primary Examiner
Patent abstract
The present invention is directed to spirocyclic compounds which are inhibitors of tryptophan hydroxylase (TPH), particularly isoform 1 (TPH1), that are useful in the treatment of diseases or disorders associated with peripheral serotonin including, for example, gastrointestinal, cardiovascular, pulmonary, inflammatory, metabolic, and low bone mass diseases, as well as serotonin syndrome, and cancer.
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