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Patent attributes
Patent Applicant
Patent Jurisdiction
Patent Number
Patent Inventor Names
Eric Brian Sjogren
Daniel R. Goldberg
Stéphane De Lombaert
Andrew Scribner
Kenneth Brameld
Date of Patent
September 19, 2023
Patent Application Number
17201750
Date Filed
March 15, 2021
Patent Citations
...
Patent Primary Examiner
CPC Code
Patent abstract
The present invention is directed to spirocyclic compounds which are inhibitors of tryptophan hydroxylase (TPH), particularly isoform 1 (TPH1), that are useful in the treatment of diseases or disorders associated with peripheral serotonin including, for example, gastrointestinal, cardiovascular, pulmonary, inflammatory, metabolic, and low bone mass diseases, as well as serotonin syndrome, and cancer.
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