Is a
Patent attributes
Patent Jurisdiction
Patent Number
Date of Patent
July 16, 2019
Patent Application Number
15978361
Date Filed
May 14, 2018
Patent Citations Received
Patent Primary Examiner
Patent abstract
The present invention is directed to spirocyclic compounds which are inhibitors of tryptophan hydroxylase (TPH), particularly isoform 1 (TPH1), that are useful in the treatment of diseases or disorders associated with peripheral serotonin including, for example, gastrointestinal, cardiovascular, pulmonary, inflammatory, metabolic, and low bone mass diseases, as well as serotonin syndrome, and cancer.
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