Is a
Patent attributes
Patent Jurisdiction
Patent Number
Patent Inventor Names
Kenneth Brameld0
Daniel R. Goldberg0
Eric Brian Sjogren0
Stéphane De Lombaert0
Andrew Scribner0
Date of Patent
August 14, 2018
0Patent Application Number
156450540
Date Filed
July 10, 2017
0Patent Citations Received
Patent Primary Examiner
Patent abstract
The present invention is directed to spirocyclic compounds which are inhibitors of tryptophan hydroxylase (TPH), particularly isoform 1 (TPH1), that are useful in the treatment of diseases or disorders associated with peripheral serotonin including, for example, gastrointestinal, cardiovascular, pulmonary, inflammatory, metabolic, and low bone mass diseases, as well as serotonin syndrome, and cancer.
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