Is a
Patent attributes
Patent Jurisdiction
Patent Number
Patent Inventor Names
Kenneth Brameld0
Stéphane De Lombaert0
Andrew Scribner0
Daniel R. Goldberg0
Eric Brian Sjogren0
Date of Patent
March 16, 2021
0Patent Application Number
168505420
Date Filed
April 16, 2020
0Patent Citations
Patent Citations Received
Patent Primary Examiner
Patent abstract
The present invention is directed to spirocyclic compounds which are inhibitors of tryptophan hydroxylase (TPH), particularly isoform 1 (TPH1), that are useful in the treatment of diseases or disorders associated with peripheral serotonin including, for example, gastrointestinal, cardiovascular, pulmonary, inflammatory, metabolic, and low bone mass diseases, as well as serotonin syndrome, and cancer.
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