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US Patent 10350208 Spirocyclic compounds as tryptophan hydroxylase inhibitors

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Patent abstract

The present invention is directed to spirocyclic compounds which are inhibitors of tryptophan hydroxylase (TPH), particularly isoform 1 (TPH1), that are useful in the treatment of diseases or disorders associated with peripheral serotonin including, for example, gastrointestinal, cardiovascular, pulmonary, inflammatory, metabolic, and low bone mass diseases, as well as serotonin syndrome, and cancer.

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Patent Citations Received
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US Patent 11759462 Spirocyclic compounds as tryptophan hydroxylase inhibitors
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https://pdfpiw.uspto.gov/.piw?Docid=1035020800
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Patent Citations Received
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US Patent 11607413 Dosage regime and method for treating pulmonary arterial hypertension
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https://pdfpiw.uspto.gov/.piw?Docid=10350208
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Patent citations received
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US Patent 10946018 Spirocyclic compounds as tryptophan hydroxylase inhibitors
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 US Patent 10350208 Spirocyclic compounds as tryptophan hydroxylase inhibitors

Infobox
Is a
Patent
Patent
Patent jurisdiction
United States Patent and Trademark Office
United States Patent and Trademark Office
Patent number
10350208
Date of patent
July 16, 2019
Patent application number
15978361
Date Filed
May 14, 2018
Patent citations
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US Patent 10045988 Spirocyclic compounds as tryptophan hydroxylase inhibitors
Patent primary examiner
‌
Kahsay Habte

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