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US Patent 9643922 MIF modulators

Patent 9643922 was granted and assigned to Yale University on May, 2017 by the United States Patent and Trademark Office.

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Is a

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Patent attributes

Current Assignee

Yale University

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Patent Jurisdiction

United States Patent and Trademark Office

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Patent Number

Patent Inventor Names

Richard J. Bucala0

William L. Jorgensen0

Date of Patent

May 9, 2017

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Patent Application Number

127734300

Date Filed

May 4, 2010

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Patent Citations Received

US Patent 11760756 Crystalline form of a PD-1/PD-L1 inhibitor

US Patent 11874276 STING levels as a biomarker for cancer immunotherapy

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US Patent 11780836 Process of preparing a PD-1/PD-L1 inhibitor

US Patent 11787793 Heterocyclic compounds as immunomodulators

US Patent 11866434 Process for making a PD-1/PD-L1 inhibitor and salts and crystalline forms thereof

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US Patent 11866435 Heterocyclic compounds as immunomodulators

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US Patent 11866451 Salts and crystalline forms of a PD-1/PD-L1 inhibitor

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US Patent 12084443 Process of preparing a PD-1/PD-L1 inhibitor

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Patent Primary Examiner

Shobha Kantamneni

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Patent abstract

The invention provides novel heterocyclic compounds, pharmaceutical compositions and methods of treatment that modulate levels of MIF expression and treat disorders associated with high or low levels of MIF expression.

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