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US Patent 9809817 Oligonucleotide compounds for targeting huntingtin mRNA

Patent 9809817 was granted and assigned to University of Massachusetts on November, 2017 by the United States Patent and Trademark Office.

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Patent

Patent attributes

Patent Applicant

University of Massachusetts

Current Assignee

University of Massachusetts

Patent Jurisdiction

United States Patent and Trademark Office

Patent Number

9809817

Patent Inventor Names

Julia Alterman0

Neil Aronin0

Anastasia Khvorova0

Date of Patent

November 7, 2017

Patent Application Number

15089319

Date Filed

April 1, 2016

Patent Citations Received

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US Patent 12077755 Bioactive conjugates for oligonucleotide delivery

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US Patent 11753638 Conjugated oligonucleotides

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US Patent 11767527 Modified oligonucleotides targeting SNPs

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US Patent 11993774 Huntingtin (HTT) iRNA agent compositions and methods of use thereof

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US Patent 12006499 Una amidites and uses thereof

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US Patent 12024706 Modified oligonucleotides targeting SNPs

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US Patent 11702659 Optimized anti-FLT1 oligonucleotide compounds for treatment of preeclampsia and other angiogenic disorders

Patent Primary Examiner

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Tracy Vivlemore

Patent abstract

This disclosure relates to novel huntingtin targets. Novel oligonucleotides for the treatment of Huntington's disease are also provided.

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